Advertisement
< Vol. 14 Issue 3 | Jul-Sep 2013 | pp. 209 - 306

Early experience with a newly developed electrospun polycarbonate-urethane vascular graft for hemodialysis access

Early experience with a newly developed electrospun polycarbonate-urethane vascular graft for hemodialysis access

J Vasc Access 2013; 14(3): 252 - 256

Article Type: ORIGINAL ARTICLE

DOI:10.5301/jva.5000128

Authors

Mariano Ferraresso, Silvio Bertoli, Paolo Nobili, Ettore Maria Bortolani

Abstract

Purpose: In this pilot study, we tested a newly developed electrospun multilayered, self-sealing graft, AVflo™, specifically designed for early hemodialysis access. 
Methods: Ten eligible consenting patients had a polycarbonate-urethane graft (AVflo™) implanted and were followed up prospectively for at least six months. Performance measures included graft patency, complications and time to first cannulation. Mean age of the patients was 66.7 ± 10 years. Chronic glomerulonephritis was the most common cause of renal failure. A total of 70% of the patients had a history of previous vascular access and 40% history of minimally invasive radiologic procedures for patency maintenance. In 40% of the cases the need for AV graft implantation was because of recurrent infections from permanent catheter for dialysis. Seven grafts were placed in the upper arm and three in the thigh. Mean follow up was 230 ± 75 days. 
Results: There were no systemic or local reactions to the graft and we did not report any graft infections. Two grafts thrombosed because of severe bleeding post-cannulation due to an incorrect needle puncture. Both grafts were successfully thrombectomized. Primary and secondary patency rates at six months were 60% and 78%, respectively. These patency rates were comparable to those reported for other polyether-urethane and ePTFE grafts. Median time to first cannulation was seven days (3-21) and all puncture sites sealed in less than five minutes.

Article History

  • • Accepted on 25/10/2012
  • • Available online on 21/01/2013
  • • Published in print on 01/10/2013

This article is available as full text PDF.

  • If you are a Subscriber, please log in now.

  • Article price: Eur 36,00
  • You will be granted access to the article for 72 hours and you will be able to download any format (PDF or ePUB). The article will be available in your login area under "My PayPerView". You will need to register a new account (unless you already own an account with this journal), and you will be guided through our online shop. Online purchases are paid by Credit Card through PayPal.
  • If you are not a Subscriber you may:
  • Subscribe to this journal
  • Unlimited access to all our archives, 24 hour a day, every day of the week.

Authors

  • Ferraresso, Mariano [PubMed] [Google Scholar]
    Division of General Surgery, Ospedale San Giuseppe-IRCCS Multimedica Milan - Italy and Department of Clinical Sciences and Community Health, University of Milan, Milan - Italy
  • Bertoli, Silvio [PubMed] [Google Scholar]
    Nephrology and Dialysis Unit, Ospedale Sesto S. Giovanni-IRCCS Multimedica, Milan - Italy
  • Nobili, Paolo [PubMed] [Google Scholar]
    Division of General Surgery, Ospedale San Giuseppe-IRCCS Multimedica Milan - Italy
  • Bortolani, Ettore Maria [PubMed] [Google Scholar]
    Division of General Surgery, Ospedale San Giuseppe-IRCCS Multimedica Milan - Italy and Department of Clinical Sciences and Community Health, University of Milan, Milan - Italy

Article usage statistics

The blue line displays unique views in the time frame indicated.
The yellow line displays unique downloads.
Views and downloads are counted only once per session.

No supplementary material is available for this article.