The effect of peripherally inserted central catheter (PICC) valve technology on catheter occlusion rates - The ‘ELeCTRiC’ study
The effect of peripherally inserted central catheter (PICC) valve technology on catheter occlusion rates - The ‘ELeCTRiC’ study
J Vasc Access 2012; 13(4): 421 - 425
DOI:10.5301/jva.5000071
Authors
Andrew J. Johnston, Carmel T. Streater, Remy Noorani, Joanne L. Crofts, Aldwin B. Del Mundo, Richard A. Parker
Abstract
Purpose: Peripherally Inserted Central Catheters (PICCs) are increasingly being used to provide short to medium-term central venous access. The current study was designed to test the hypothesis that PICC valve technology does not influence PICC occlusion rates. Methods: Intensive care unit (ICU) patients who required a PICC were randomized to one of three types of dual lumen PICC (open ended non-valved, Groshong valve, PASV valve). PICC occlusions were recorded and managed with a protocol that used urokinase. Results: A total of 102 patients were recruited to the study. The overall risk of occlusion per catheter was 35% (95% CI 26% to 44%). The overall rate of occlusion was 76 occlusions per 1000 catheter days (95% CI 61 to 95). Presence or type of valve did not significantly influence this rate (open-ended non-valved PICC 38% of catheters, 79 occlusions per 1000 catheter days; Groshong 38% of catheters, 60 occlusions per 1000 catheter days; PASV 27% of catheters, 99 occlusions per 1000 catheter days). The dose of urokinase required to treat PICC occlusions did not significantly differ between PICC types. Conclusions: Valved PICCs do not appear to influence PICC occlusion rates.
Article History
- • Accepted on 15/03/2012
- • Available online on 02/04/2012
- • Published in print on 16/01/2013
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Authors
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Johnston, Andrew J. [PubMed] [Google Scholar]
Vascular Access Team, Cambridge University Hospitals NHS Foundation Trust, Cambridge and John Farman Intensive Care Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge - UK
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Streater, Carmel T. [PubMed] [Google Scholar]
Vascular Access Team, Cambridge University Hospitals NHS Foundation Trust, Cambridge - UK
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Noorani, Remy [PubMed] [Google Scholar]
Vascular Access Team, Cambridge University Hospitals NHS Foundation Trust, Cambridge - UK
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Crofts, Joanne L. [PubMed] [Google Scholar]
Vascular Access Team, Cambridge University Hospitals NHS Foundation Trust, Cambridge - UK
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Del Mundo, Aldwin B. [PubMed] [Google Scholar]
Vascular Access Team, Cambridge University Hospitals NHS Foundation Trust, Cambridge - UK
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Parker, Richard A. [PubMed] [Google Scholar]
Centre for Applied Medical Statistics, University of Cambridge, Cambridge - UK