Totally implantable central venous access ports in patients with cystic fibrosis: a multicenter prospective cohort study
Totally implantable central venous access ports in patients with cystic fibrosis: a multicenter prospective cohort study
J Vasc Access 2012; 13(3): 290 - 295
DOI:10.5301/jva.5000036
Authors
Alberto Dal Molin, Dino Stefano Di Massimo, Cesare Braggion, Sofia Bisogni, Elena Rizzi, Ciro D’Orazio, Maria Vittoria Di Toppa, Federico Alghisi, Simona Cristadoro, Vincenzo Carnovale, Gabriella Festa, Serena Rampini, Carla Colombo, Anna Oneta, Maria Lucia Furnari, Maria Antonietta Calamia, Maria Luisa Zunino, Giuseppe Tuccio, Vincenzo Spadea, Barbara Messore, Bianca Grosso, Filippo Festini
Abstract
Purpose: The aim of this study was to assess the incidence of late onset complications of totally implantable venous access devices (TIVAD) in patients with cystic fibrosis (CF) and to investigate possible associations between the rate of complications and different policies of TIVAD management. Methods: A multicenter prospective cohort study was performed in 11 Italian CF Centers. Patients with CF and a TIVAD were recruited and followed-up. Results: The study commenced on May 2008 and ended on September 2010. Eighty subjects were studied (77.5% women - mean age 27.2 years). Eighteen late complications of ports were observed (22.5%; incidence 0.96 per 1000 days of observation): three lumen occlusions, seven catheter-related infections , three port-related venous thrombosis, in addition to five other complications. A statistically significant association was found between the onset of catheter-related infection and the presence of CF-related diabetes (CFRD) (P=.0064) Conclusions: Our data suggest that TIVADs represent a safe and effective device for the intermittent IV administration of drugs in people with CF. However, people with CFRD have a higher risk of developing TIVAD-related infection.
Article History
- • Accepted on 28/11/2011
- • Available online on 10/01/2012
- • Published in print on 28/09/2012
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Authors
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Dal Molin, Alberto [PubMed] [Google Scholar]
Nursing School, Biella Hospital, University of Piemonte Orientale - Italy
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Di Massimo, Dino Stefano [PubMed] [Google Scholar]
Biella Hospital, Italy
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Braggion, Cesare [PubMed] [Google Scholar]
CF Center of Florence, “A. Meyer Children’s Hospital”, Florence - Italy
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Bisogni, Sofia [PubMed] [Google Scholar]
CF Center of Florence, “A. Meyer Children’s Hospital”, Florence - Italy
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Rizzi, Elena [PubMed] [Google Scholar]
CF Center of Verona - Italy
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D’Orazio, Ciro [PubMed] [Google Scholar]
CF Center of Verona - Italy
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Di Toppa, Maria Vittoria [PubMed] [Google Scholar]
CF Center of Rome, Bambino Gesù Children’s Hospital, Rome - Italy
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Alghisi, Federico [PubMed] [Google Scholar]
CF Center of Rome, Bambino Gesù Children’s Hospital, Rome - Italy
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Cristadoro, Simona [PubMed] [Google Scholar]
CF Center of Messina, University Hospital “G.Martino” Messina - Italy
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Carnovale, Vincenzo [PubMed] [Google Scholar]
CF Center of Naples (adult Center), University Hospital “Federico II” of Naples - Italy
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Festa, Gabriella [PubMed] [Google Scholar]
CF Center of Naples (adult Center), University Hospital “Federico II” of Naples - Italy
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Rampini, Serena [PubMed] [Google Scholar]
CF Center, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, University of Milan - Italy
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Colombo, Carla [PubMed] [Google Scholar]
CF Center, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, University of Milan - Italy
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Oneta, Anna [PubMed] [Google Scholar]
CF Center (adult Center), Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, University of Milan - Italy
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Furnari, Maria Lucia [PubMed] [Google Scholar]
CF Center of Palermo - Children Hospital ‘Di Cristina’, Palermo - Italy
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Calamia, Maria Antonietta [PubMed] [Google Scholar]
CF Center of Palermo - Children Hospital ‘Di Cristina’, Palermo - Italy
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Zunino, Maria Luisa [PubMed] [Google Scholar]
CF Center of Genova - G. Gaslini Children’s Hospital, Genova - Italy
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Tuccio, Giuseppe [PubMed] [Google Scholar]
CF Center of Soverato - Soverato Hospital, Catanzaro - Italy
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Spadea, Vincenzo [PubMed] [Google Scholar]
CF Center of Soverato - Soverato Hospital, Catanzaro - Italy
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Messore, Barbara [PubMed] [Google Scholar]
CF Center of Turin (adult Center) - AOU San Luigi, Orbassano, Turin - Italy
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Grosso, Bianca [PubMed] [Google Scholar]
CF Center of Turin (adult Center) - AOU San Luigi, Orbassano, Turin - Italy
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Festini, Filippo [PubMed] [Google Scholar]
Department of Sciences of Women’s and Children’s Health, University of Florence, Florence - Italy